46 Normal - Zone blitz
Shift Line and Backers to the right side of the screen.
Contain the ROLB (left side of screen)
Control the RDT (left side of screen)
This should shut down most runs to the right. If they run to the left outside, a good LB (Like Keith Bulluck for me) should close and hold them to a minimal gain and if they go to the inside left, just cut them of with the RDT and either tackle him or make the run flow to the middle where the tacklers will be.