Boy, that does suck. But all is not lost. Use a couple good Offensive Tackles in that position. Then use the OT's to block for you.
Put one in a split backfield to keep the heat out. Motion one into the A Gap for an up the gut run. Motion one into the gap that the blitz is coming from. Look for a good pitch that puts the TE (OTSub) out in front of the pitch. Same with a screen.
Put a couple tackles on one side of the Power O, run it a few times, then when you think, they think they got you figured out. Run the other way, away from your OT subs.
If you don't have any good backup Offensive Tackles, move a backup guard over to tackle to free one up. Or move a backup center to guard and guard to tackle, to get one. Just make sure in the end to maintain a good or better offensive Line.
Also you can get a fullback and put him in that spot. I hear Lorenzo Neal is available. Anyway just a few suggestions, study yor depth chart, study your player ratings, practice the new wrinkles.
Good Luck
If you want to send me your team and roster, go ahead, I might be able to help.