I tried the 3-4 with them once and I found a nice setup
ROLB: Freeney
MLBs: Brackett, Session
LOLB: Mathis
RE: Fili Moala
LE: Raheem Brock
DT: Eric Foster
They lack strength, but since there are not a lot of double teams in the game, you can have this light DL in a 3-4. Freeney and Mathis are very fast, that'll help a lot from their OLB spots.