You have to be versatile with your playcalling regardless, 4-6 is a beast against the run, but I find it to be pretty weak against the pass. If they have anymore then 2 receivers I wouldn't recommend using it. But I will give you 2 plays to start out with sense I'm also a Vikings fan! lol. Dime Flat Cover 2 - Used obviously in passing situations mainy short passes, be sure to go to kevin and pat williams and hit X and down on the left stick or with xbox A and down on the left stick. Make your DE's especially Jared Allen blitz the outside, and what that does is force them out of the pocket because of Pat And Kevin and then sometimes allows for easy sacks by Jared Allen or Ray Edwards. I would be Jared Allen if I where you because manually controlling him puts alot more pressure on the QB and forces the opposition to make mistakes. Now, if it's a running play, I would come out in a 4-6 man to man scheme like the 2 Man under, hit R1 and up on the RIGHT stick or LB and up on RIGHT stick for xbox to make your MLB stay in the middle of the field. If it's a power running back hit R1 and DOWN to move your LB's closer to the LOS. If it's a speed back hit R1 and UP to spread your LB's out because usually they'll try to get to the outside. Hope these 2 plays helps.