A screen will kill any zone assuming you have a good tackle lead blocking. Against cover 2 and cover 3 running a 10-15 yard corner with a slot reciever works pretty well. With zone, it's more just about breaking down the zones though. Assuming you have time to throw you can still find a reciever or TE over the middle of the field, you just have to be patient and read the play. One other thing that works on the cover 2 is having your outside reciever run the hot route (rs up) a variation of the fade will have your reciever open on the sidelines.