if it's out of shotgun 2RB 3WR its called RB Circles.
both RB (often they use Dual HB) do those circle routes
the Z receiver (#1 receiver) does an in route
the #2 receiver does a hook
and the slot receiver does a streak
as for defending it, 1 thing that works is putting your defensive ends in mid zones, the yellow zones, and you can do that on pretty much any defensive play you want to use. 2 man under works, cover 2 can work. make sure you bring up your corners and safeties. its a quick play and a blitz killer, so get a good zone play that will catch him off guard when he tries to hit the RBs.