Dont abuse them. If u abuse them they will get burnt. Usually they will run on 1st down. What i like to do is use it on 2nd down. If its a sack it puts them in a 3rd and long. So he excepts it on 2nd down so ill fake it then run it on 3rd down. Just mix it up and keep ur opponent guessing if ur nanoing or not. Another good tip is too fake it, act like ur setting up a nano but then they drop of into coverage so maybe you can get a quick throw.