to stop the crossing routes, try blitzing. if you can get to him quick enough, he will either be sacked or make a bad throw. for the screen, you could manually give the corner or a safety a flat zone, not man. sometimes, in man, they will be picked up by the blockers. if they stay in the zone, they will hover right above and tackle welker once he gets it. or, you could manually bring defenders over to cover the screen.